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T-Series online videos - Full HD movies available to download in best quality for mobile phone, tablet and desktop, including Bollywood, Hollywood, Indian and Pakistani.Efficacy and safety of polymeric microparticles for intranasal administration of allicin: an effective natural anti-allergic compound. Allicin (diallylthiosulfinate), a major allyl isothiocyanate found in the volatile oil of Allium sativum, has been shown to exert anti-allergic effects in our previous studies. However, the poor water-solubility of allicin hindered the development of pharmaceutical preparations for the treatment of allergic diseases. In the present study, a poly(D,L-lactide) microparticle formulation (PML) was developed for intranasal administration of allicin, which was characterized in terms of its structure and properties, and its anti-allergic effects were evaluated in vivo. PML was prepared by a w/o/w emulsion solvent evaporation method and the average particle size of the microparticles was controlled to be less than 100 microm. Furthermore, the surface characteristics of PML and the release profiles of allicin from the microparticles were determined by various analyses. In addition, in vitro cytotoxicity against C6 rat glial cells was performed to evaluate the safety of allicin. PML was characterized by X-ray diffraction (XRD) and differential scanning calorimetry (DSC), which indicated that PML was an amorphous phase in nature. The release rate of allicin from PML increased as the microparticles degraded, which reached the peak at the 4th week after the application and then gradually decreased. The pharmacokinetic parameters of allicin from PML were also evaluated and found to be better than that of raw allicin. In addition, the oral administration of PML in BALB/c mice was safe with no apparent side effects. Compared with raw allicin, PML was found to be effective and safe and therefore, was considered to be a potential strategy for the treatment of allergic diseases.Q: How to use ArrayList.iterator in a loop? I have a function that will read and print the data in the ArrayList and then read the data and remove it. private void printData(){ for (int i = 0; i

 

 

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